Biography
Dinh-Dung Nguyen graduated with Distinction in Biotechnology from Sheffield Hallam University in 2015. He then began his career as a Medical Specialist at the Vinmec Research Institute of Stem Cell and Gene Technology. In 2018, he returned to the UK to pursue his doctoral degree, completing his PhD in Biomedical Science at Northumbria University in 2022. Following his PhD, he rejoined the Vinmec Healthcare System as part of the High-tech Centre. In 2023, he officially became a researcher at the Vinmec-VinUni Research Institute of Immunology, joining a key group of scientists studying cancer immunology.
Dinh’s strengths lie in molecular and cell biology, particularly in the field of antigen presentation. His primary research interests involve applying gene-editing technologies, especially CRISPR-Cas9 platforms, to study human disease mechanisms and develop novel immunotherapies and treatments for genetic diseases.
Gene-editing; Gene Therapy; Immunology; Antigen Presentation; Molecular Biology
1. Nguyen DD, Ho N, Dover LG, Vo A, Ly H, Doan P, et al. Novel Variant and Known Mutation in 23S rRNA Gene of Mycoplasma pneumoniae, Northern Vietnam, 2023. Emerg Infect Dis. 2024;30(5):1034-1036. https://doi.org/10.3201/eid3005.231632
2. Nguyen DD, Phung LT, Thanh Tran HT, et al. Molecular subtypes of Adenovirus-associated acute respiratory infection outbreak in children in Northern Vietnam and risk factors of more severe cases. PLoS Negl Trop Dis. 2023;17(11):e0011311. Published 2023 Nov 7. doi:10.1371/journal.pntd.0011311.
3. Izabela Lenart, Linh-Huyen Truong, Dinh-Dung Nguyen, Olga Cugaj, Edward Tsao, Branca Pereira, Kirsty McHugh, Paul Bowness, Neil Blake, Simon J. Powis, Keith Gould, Darren Nesbeth, and Antony N. Antoniou (2022). Peptide binding groove F pocket sequences influence MHC class I single chain trimeric molecule folding. Frontier in Immunology.
4. Le, T., Tran, N. T., Dao, T., Nguyen, D. D., Do, H. D., Ha, T. L., Kühn, R., Nguyen, T. L., Rajewsky, K., & Chu, V. T. (2019). Efficient and Precise CRISPR/Cas9-Mediated MECP2 Modifications in Human-Induced Pluripotent Stem Cells. Frontiers in Genetics.
5. Dinh-Dung Nguyen, Andrew Nelson, Anh Vo, Sharon Cookson, Darren Smith, Stephen Todryk, Simon Powis and Antony N. Antoniou. “Using CRISPR/Cas9 to present MHC class I peptides: A proof of principle study in the design of ex vivo personalized vaccines”. Nature methods. [Submitting manuscript]
6. Dinh-Dung Nguyen, Olga Cugaj, Simon Powis and Antony N. Antoniou. Targeting changes in specific sequences in MHC class I molecules using CRISPR-Cas9 as a novel approach for potential immunotherapies. [Writing manuscript]
7. Ho K. Hoa, Nguyen T. Trang, Nguyen T. Tuan, Nguyen T.T. Tam, Nguyen D. Dung and Le H. Thang (2016). Application of DNA Microarray in detecting genetic deafness mutation in Vietnamese children. Vietnam Medical Journal
VOS Poster for the Workshop on Medical Applications of Organoids – 2nd Prize – 2024
Vingroup PhD Scholarship – 2018
Top 5, Fujio Cup Quiz on Stem cell and regenerative medicine -2017
Frontrunner Leadership- 2015
Regional Scholarship in recognition of academic excellence – 2014
Transform Together Scholarship – 2010
MOET Fully funded Undergraduate Scholarship in UK – 2010