Biography
Mr. Vu Minh Duc received the BSc. degree in biology from Vietnam National University at Ha Noi in 2003 and the MSc. degrees in biology from Thai Nguyen University in 2009. He was a highly skilled Molecular Genetics Specialist at Division of Genomic Medicine, Vinmec Hi-Tech Center – Vinmec Healthcare System. His career is dedicated to advancing precision medicine through genetic research and testing. He has a strong background as a researcher at the University of Science, Vietnam National University; Institute of Biotechnology; Max Delbrueck Center for Molecular Medicine and Vinmec Research Institute of Stem Cell and Gene Technology (VRISG). He has also held positions at the Foundation for Innovative New Diagnosis, and Biomedic JSC.
Mr. Duc’s expertise lies in NGS-based techniques for genetic disease analysis and cancer genetic profiling. He is experienced in genetic testing for hereditary cancer screening and genetic disease diagnosis using next-generation sequencing (NGS) and is well-versed in operating Illumina platforms. He has extensive experience in validating and implementing genetic testing methods for various cancers, utilizing advanced NGS panels. He has been involved in numerous research projects, including studies on autism spectrum disorder, development of a genomic variant database for the Vietnamese population, and R&D projects focused on cancer genetic testing.
Life science, Cancer immunology
1. Hoang TH, Vu DM, Vu GM, Nguyen TK, Do NM, Duong VC, Pham TL, Tran MH, Khanh Nguyen LT, Han HTT, Can TT, Pham TH, Pham TD, Nguyen TH, Do HP, Vo NS, Nguyen XH. A study of genetic variants associated with skin traits in the Vietnamese population. BMC Genomics. 2024 Jan 11;25(1):52. doi: 10.1186/s12864-023-09932-y. PMID: 38212682; PMCID: PMC10785522.
2. Vu DM, Nguyen VT, Nguyen TH, Do PTX, Dao HH, Hai DX, Le NT, Nguyen XH, Than UTT. Effects of extracellular vesicles secreted by TGFβ-stimulated umbilical cord mesenchymal stem cells on skin fibroblasts by promoting fibroblast migration and ECM protein production. Biomedicines. 2022 Jul 27;10(8):1810. doi: 10.3390/biomedicines10081810. PMID: 36009357; PMCID: PMC9405311.
3. Nguyen LT, Hoang DM, Nguyen KT, Bui DM, Nguyen HT, Le HTA, Hoang VT, Bui HTH, Dam PTM, Hoang XTA, Ngo ATL, Le HM, Phung NY, Vu DM, Duong TT, Nguyen TD, Ha LT, Bui HTP, Nguyen HK, Heke M, Bui AV. Type 2 diabetes mellitus duration and obesity alter the efficacy of autologously transplanted bone marrow-derived mesenchymal stem/stromal cells. Stem Cells Transl Med. 2021 Sep;10(9):1266-78. doi: 10.1002/sctm.20-0506. Epub 2021 Jun 3. PMID: 34080789; PMCID: PMC8380443.
4. Tran KT, Le VS, Bui HTP, Do DH, Ly HTT, Nguyen HT, Dao LTM, Nguyen TH, Vu DM, Ha LT, Le HTT, Mukhopadhyay A, Nguyen LT. Genetic landscape of autism spectrum disorder in Vietnamese children. Sci Rep. 2020 Mar 19;10(1):5034. doi: 10.1038/s41598-020-61695-8. PMID: 32193494; PMCID: PMC7081304.
5. Hoang DH, Nguyen TD, Nguyen HP, Nguyen XH, Do PTX, Dang VD, Dam PTM, Bui HTH, Trinh MQ, Vu DM, Hoang NTM, Thanh LN, Than UTT. Differential wound healing capacity of mesenchymal stem cell-derived exosomes originated from bone marrow, adipose tissue and umbilical cord under serum- and xeno-free condition. Front Mol Biosci. 2020 Jun 24;7:119. doi: 10.3389/fmolb.2020.00119. PMID: 32671095; PMCID: PMC7327117.
6. Nguyen-Hoai T, Kobelt D, Hohn O, Vu MD, Schlag PM, Dörken B, Norley S, Lipp M, Walther W, Pezzutto A, Westermann J. HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model: Gene gun is superior to jet injector in inducing CTL responses and protective immunity. Oncoimmunology. 2012 Dec 1;1(9):1537-45. doi: 10.4161/onci.22563. PMID: 23264900; PMCID: PMC3525609.
7. Nguyen-Hoai T, Hohn O, Vu MD, Baldenhofer G, Sayed Ahmed MS, Dörken B, Norley S, Lipp M, Pezzutto A, Westermann J. CCL19 as an adjuvant for intradermal gene gun immunization in a Her2/neu mouse tumor model: improved vaccine efficacy and a role for B cells as APC. Cancer Gene Ther. 2012 Dec;19(12):880-7. doi: 10.1038/cgt.2012.78. Epub 2012 Oct 26.
8. Nguyen-Hoai T, Baldenhofer G, Sayed Ahmed MS, Pham-Duc M, Vu MD, Lipp M, Dörken B, Pezzutto A, Westermann J. CCL21 (SLC) improves tumor protection by a DNA vaccine in a Her2/neu mouse tumor model. Cancer Gene Ther. 2012 Jan;19(1):69-76. doi: 10.1038/cgt.2011.69. Epub 2011 Oct 14. PMID: 21997231.